By DAILY MAIL REPORTER
Type 2: While the disease mainly affects the middle aged, a study suggests that susceptibility could be programmed into the cells of an unborn baby
A poor diet during pregnancy may increase the risk of a woman’s children and grandchildren developing type 2 diabetes in later life.
The disease mainly affects the middle aged, but a study suggests that susceptibility could be programmed into the cells of an unborn baby if his or her mother eats unhealthily.
In theory, this diabetes vulnerability gene could then be passed down to the child’s offspring and future generations.
Cambridge University scientists pinpointed the gene in tests on rats that showed it was reprogrammed in the womb by a protein-deficient diet given to the mother.
Other research suggests a range of unbalanced diets may result in an increased risk of diabetes, not just protein-restricted ones.
The Cambridge researchers focused on a 'master regulator' metabolism gene important in the development of the pancreas in the womb and its ability to produce insulin
The Cambridge team, whose work is published in the journal Proceedings Of The National Academy Of Sciences, focused on a ‘master regulator’ metabolism gene that is important both in the development of the pancreas in the womb and its ability to produce insulin.
Feeding mother rats a low-protein diet reduced the gene’s activity, decreased insulin production and made the offspring prone to developing type 2 diabetes in later life.
The scientists say it is likely humans would be affected in a similar way.
source: dailymail
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